Downstream Process Development Senior Scientist

2 days ago

Athens, Attica, Greece Demo S.A. Full time €104,000 - €130,878 per year

At DEMO SA, one of the world's largest pharmaceutical manufacturers in injectable facilities, our new Biotechnology Center in Athens, Kryoneri is now fully operational.

Biotechnology is transforming healthcare, and DEMO is at the forefront with cutting-edge research and innovation. As we continue to grow, we are looking for a high-caliber DSP Senior Scientist to join our team.

Main duties and responsibilities:

  • Plan and execute downstream process development projects, including chromatography and filtration strategies.
  • Design, plan, and perform experiments to identify Critical Process Parameters (CPPs) and their impact on Critical Quality Attributes (CQAs).
  • Apply advanced statistical and experimental design methodologies (e.g., DoE) to optimize process performance.
  • Conduct process characterization studies, such as viral clearance, resin reuse, and process limit evaluations.
  • Collaborate with cross-functional teams to scale processes from lab to pilot and commercial scale.
  • Author and review technical documentation, including development reports, protocols, and support regulatory submissions.
  • Provide technical support during technology transfer and scale-up.
  • Stay at the forefront of innovation by monitoring industry trends and integrating novel technologies into our workflows.

Requirements

  • PhD or MSc in Biochemical Engineering, Biotechnology, Biochemistry, or related field.
  •  5+ years of hands-on experience in downstream process development within the biopharmaceutical industry.
  • Expertise in chromatography, filtration, and process characterization techniques.
  • Strong grasp of DoE principles and statistical analysis tools (e.g., JMP, Minitab).
  • Experience with GMP environments, regulatory expectations, and tech transfer.
  • Excellent problem-solving skills and a passion for data-driven decision-making and a team player.

Benefits

The Company offers competitive remuneration, continuous learning and development opportunities, and a friendly and challenging working environment.

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